Intussusception (medical disorder): Difference between revisions

→‎Pathophysiology: task, replaced: American journal of emergency medicine → American Journal of Emergency Medicine
(not needed as in body)
m (→‎Pathophysiology: task, replaced: American journal of emergency medicine → American Journal of Emergency Medicine)
An anatomic ''lead point'' (that is, a piece of intestinal tissue that protrudes into the bowel lumen) is present in approximately 10% of intussusceptions.<ref>[ Chapter X.4. Intussusception ] {{webarchive|url= |date=2012-08-26 }} from Case Based Pediatrics For Medical Students and Residents, by Lynette L. Young, MD. Department of Pediatrics, University of Hawaii John A. Burns School of Medicine. December 2002</ref>
The trapped section of bowel may have its blood supply cut off, which causes [[ischemia]] (lack of oxygen in the tissues). The [[mucosa]] (gut lining) is very sensitive to [[ischemia]], and responds by sloughing off into the gut. This creates the classically described "red currant jelly" stool, which is a mixture of sloughed mucosa, blood, and mucus.<ref name=Toso>{{cite journal|vauthors=Toso C, Erne M, Lenzlinger PM, Schmid JF, Büchel H, Melcher G, Morel P|title=Intussusception as a cause of bowel obstruction in adults|journal=Swiss Med Wkly|date=2005|volume=135|issue=5–6|pages=87–90|pmid=15729613|url=|deadurl=no|archiveurl=|archivedate=2015-09-24|df=}}</ref> A study reported that in actuality, only a minority of children with intussusception had stools that could be described as "red currant jelly", and hence intussusception should be considered in the differential diagnosis of children passing ''any'' type of bloody stool.<ref>{{cite journal|last=Yamamoto|first=LG|author2=Morita, SY |author3=Boychuk, RB |author4=Inaba, AS |author5=Rosen, LM |author6=Yee, LL |author7= Young, LL |title=Stool appearance in intussusception: assessing the value of the term "currant jelly."|journal=The American journalJournal of emergencyEmergency medicineMedicine|date=May 1997|volume=15|issue=3|pages=293–8|pmid=9148991 |doi=10.1016/s0735-6757(97)90019-x}}</ref>