ChEBI: Difference between revisions

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'''Chemical Entities of Biological Interest''', also known as '''ChEBI''',<ref name=pmid19854951/><ref name=pmid17932057>{{cite journal |pages=D344–50 |doi=10.1093/nar/gkm791 |title=ChEBI: A database and ontology for chemical entities of biological interest |year=2007 |last1=Degtyarenko |first1=K. |last2=De Matos |first2=P. |last3=Ennis |first3=M. |last4=Hastings |first4=J. |last5=Zbinden |first5=M. |last6=McNaught |first6=A. |last7=Alcantara |first7=R. |last8=Darsow |first8=M. |last9=Guedj |first9=M. |last10=Ashburner |first10=M. |journal=Nucleic Acids Research |volume=36 |pmid=17932057 |issue=Database issue |pmc=2238832|display-authors=8 }}</ref> is a database and [[Ontology (information science)|ontology]] of [[molecular entity|molecular entities]] focused on 'small' chemical compounds, that is part of the [[Open Biomedical Ontologies]] effort. The term "molecular entity" refers to any "constitutionally or isotopically distinct [[atom]], [[molecule]], [[ion]], [[ion pair]], [[Radical (chemistry)|radical]], [[radical ion]], [[complex (chemistry)|complex]], [[conformational isomerism|conformer]], etc., identifiable as a separately distinguishable entity".<ref>{{GoldBookRef|title=molecular entity|file=M03986}}</ref> The molecular entities in question are either products of nature or synthetic products which have potential bioactivity. Molecules directly encoded by the genome, such as [[nucleic acids]], [[proteins]] and [[peptides]] derived from proteins by [[proteolytic]] cleavage, are not as a rule included in ChEBI.
 
ChEBI uses [[IUPAC nomenclature|nomenclature]], symbolism and terminology endorsed by the [[IUPAC|International Union of Pure and Applied Chemistry]] (IUPAC) and Nomenclature Committee of the [[International Union of Biochemistry and Molecular Biology]] (NC-IUBMB).