ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 is a protein in humans that is encoded by the ATP6V0D2 gene. [5] It is part of proton pumps in the plasma membranes of osteoclasts and aids with extracellular acidification in bone resorption. [6]

ATP6V0D2
Identifiers
AliasesATP6V0D2, ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2, ATP6D2, VMA6, ATPase H+ transporting V0 subunit d2
External IDsMGI: 1924415 HomoloGene: 72090 GeneCards: ATP6V0D2
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for ATP6V0D2
Genomic location for ATP6V0D2
Band8q21.3Start85,987,323 bp[1]
End86,154,225 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152565

NM_175406

RefSeq (protein)

NP_689778

NP_780615

Location (UCSC)Chr 8: 85.99 – 86.15 MbChr 4: 19.88 – 19.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147614 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028238 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2". Retrieved 2012-11-12.
  6. ^ Wu H, Xu G, Li YP (May 2009). "Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption". Journal of Bone and Mineral Research. 24 (5): 871–85. doi:10.1359/jbmr.081239. PMC 2672205. PMID 19113919.

External linksEdit

Further readingEdit