ATP synthase subunit s, mitochondrial is an enzyme that in humans is encoded by the ATP5S gene.[5][6][7]

DMAC2L
Identifiers
AliasesDMAC2L, ATPW, FB, HSU79253, ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B), ATP5S, distal membrane arm assembly complex 2 like
External IDsMGI: 1915305 HomoloGene: 12232 GeneCards: DMAC2L
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for DMAC2L
Genomic location for DMAC2L
Band14q21.3Start50,312,326 bp[1]
End50,335,558 bp[1]
RNA expression pattern
PBB GE ATP5S 213995 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001003803
NM_001003805
NM_015684

NM_026536
NM_001361690
NM_001361691

RefSeq (protein)

NP_001003803
NP_001003805
NP_056499

NP_080812
NP_001348619
NP_001348620

Location (UCSC)Chr 14: 50.31 – 50.34 MbChr 12: 69.72 – 69.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified.[7]

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125375 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054894 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Belogrudov GI, Hatefi Y (Feb 2002). "Factor B and the mitochondrial ATP synthase complex". J Biol Chem. 277 (8): 6097–103. doi:10.1074/jbc.M111256200. PMID 11744738.
  6. ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  7. ^ a b "Entrez Gene: ATP5S ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)".

External linksEdit

Further readingEdit