ATPase, H+/K+ transporting, nongastric, alpha polypeptide (also known as ATP12A) is a protein that in humans is encoded by the ATP12A gene.[5][6][7]

ATP12A
Identifiers
AliasesATP12A, ATP1AL1, #945, HK, ATPase H+/K+ transporting non-gastric alpha2 subunit
External IDsMGI: 1926943 HomoloGene: 68197 GeneCards: ATP12A
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for ATP12A
Genomic location for ATP12A
Band13q12.12|13q12.1-q12.3Start24,680,411 bp[1]
End24,712,493 bp[1]
RNA expression pattern
PBB GE ATP12A 207367 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001676
NM_001185085

NM_138652

RefSeq (protein)

NP_001172014
NP_001667

NP_619593

Location (UCSC)Chr 13: 24.68 – 24.71 MbChr 14: 56.37 – 56.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Contents

FunctionEdit

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H+ and K+ ions across the plasma membrane. It is also responsible for potassium absorption in various tissues.[5]

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000075673 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022229 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide".
  6. ^ Sverdlov VE, Kostina MB, Modyanov NN (March 1996). "Genomic organization of the human ATP1AL1 gene encoding a ouabain-sensitive H,K-ATPase". Genomics. 32 (3): 317–27. doi:10.1006/geno.1996.0125. PMID 8838794.
  7. ^ Yang-Feng TL, Schneider JW, Lindgren V, Shull MM, Benz EJ, Lingrel JB, Francke U (February 1988). "Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes". Genomics. 2 (2): 128–38. doi:10.1016/0888-7543(88)90094-8. PMID 2842249.

External linksEdit

Further readingEdit