Probable phospholipid-transporting ATPase IF is an enzyme that in humans is encoded by the ATP11B gene.[5][6][7]

ATP11B
Identifiers
AliasesATP11B, ATPIF, ATPIR, ATPase phospholipid transporting 11B (putative)
External IDsMGI: 1923545 HomoloGene: 32919 GeneCards: ATP11B
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for ATP11B
Genomic location for ATP11B
Band3q26.33Start182,793,503 bp[1]
End182,921,629 bp[1]
RNA expression pattern
PBB GE ATP11B 212536 at fs.png

PBB GE ATP11B gnf1h02492 at fs.png

PBB GE ATP11B gnf1h02491 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014616

NM_029570

RefSeq (protein)

NP_055431

n/a

Location (UCSC)Chr 3: 182.79 – 182.92 MbChr 3: 35.75 – 35.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Contents

FunctionEdit

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[7]

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000058063 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037400 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
  6. ^ Halleck MS, Lawler JF JR, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Newman JT, Nakanishi Y, Ando H, Weinstock D, Williamson P, Schlegel RA (Nov 1999). "Differential expression of putative transbilayer amphipath transporters". Physiological Genomics. 1 (3): 139–50. PMID 11015572.
  7. ^ a b "Entrez Gene: ATP11B ATPase, Class VI, type 11B".

External linksEdit

Further readingEdit